Details for gene set NCI_IL12-MEDIATED SIGNALING EVENTS[GSEA]

Table: GSEA Results Summary

Dataset	Set_04_DMpreB_versus_WTpreB.phenotype_DMpreB_versus_WTpreB.cls #DMpreB_versus_WTpreB
Phenotype	phenotype_DMpreB_versus_WTpreB.cls#DMpreB_versus_WTpreB
Upregulated in class	WTpreB
GeneSet	NCI_IL12-MEDIATED SIGNALING EVENTS
Enrichment Score (ES)	-0.688636
Normalized Enrichment Score (NES)	-1.7222534
Nominal p-value	0.0
FDR q-value	0.009562945
FWER p-Value	0.068

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	ARRB2	20806	1172	2.927	-0.0405	No
2	MAPK8	6459	1644	2.061	-0.0500	No
3	CD86	1660 22601	1910	1.663	-0.0514	No
4	MALT1	6274	1985	1.573	-0.0431	No
5	RAB7A	9684 5347 9683	2086	1.451	-0.0372	No
6	CHUK	23665	2157	1.372	-0.0304	No
7	IL12RB1	3916 18582	2185	1.330	-0.0215	No
8	IKBKB	4907	2775	0.746	-0.0475	No
9	IL2RB	22219	3089	0.502	-0.0605	No
10	IL18R1	14263	3136	0.468	-0.0593	No
11	EOMES	4669	3300	0.391	-0.0651	No
12	IL1R1	14264 3987	3542	0.316	-0.0757	No
13	CD3D	19473	3849	0.241	-0.0903	No
14	IL1B	14431	3902	0.230	-0.0913	No
15	IL6ST	4920	3953	0.221	-0.0923	No
16	IL4	9174	4886	0.119	-0.1417	No
17	CD4	16999	5252	0.099	-0.1607	No
18	XPO1	4172	5363	0.093	-0.1659	No
19	FBXW11	20926	5626	0.080	-0.1794	No
20	SRC	5507	5727	0.076	-0.1843	No
21	IL27	17636	7242	0.038	-0.2657	No
22	IL12RB2	17128	7245	0.038	-0.2656	No
23	IL13	20461	7270	0.037	-0.2666	No
24	GATA3	9004	7429	0.034	-0.2748	No
25	FRAP1	2468 15991	7625	0.031	-0.2851	No
26	CD3E	8714	8077	0.024	-0.3093	No
27	CCL3	20317	8171	0.022	-0.3142	No
28	IL17A	14289	8269	0.021	-0.3192	No
29	IL2	15354	8580	0.017	-0.3359	No
30	CD28	14239 4092	8632	0.016	-0.3385	No
31	CD247	4498 8715	9036	0.011	-0.3602	No
32	B2M	72 14882	9089	0.011	-0.3629	No
33	ATM	2976 19115	9513	0.005	-0.3857	No
34	NFKB2	23810	9535	0.005	-0.3868	No
35	PRF1	20011	9734	0.002	-0.3975	No
36	CCL4	1362 20730	10317	-0.005	-0.4289	No
37	IL12B	20918	10475	-0.007	-0.4373	No
38	CCR5	8754 4534	10515	-0.007	-0.4394	No
39	IL6	16895	10534	-0.008	-0.4403	No
40	TBX21	20276	10858	-0.012	-0.4576	No
41	CD3G	19139	11522	-0.022	-0.4933	No
42	IKBKG	2570 2562 4908	11885	-0.028	-0.5126	No
43	GZMA	21343	12107	-0.032	-0.5243	No
44	IL18RAP	14262	12314	-0.037	-0.5351	No
45	PIK3R1	3170	12502	-0.041	-0.5449	No
46	RIPK2	2528 15935	12517	-0.042	-0.5453	No
47	GZMB	21810	12565	-0.043	-0.5475	No
48	SPHK2	1217 1806 12155	13302	-0.065	-0.5868	No
49	PIK3CA	9562	13540	-0.075	-0.5990	No
50	ATF2	4418 2759	13664	-0.081	-0.6050	No
51	TNF	23004	13668	-0.082	-0.6046	No
52	CD8B	4502 17418	13714	-0.084	-0.6063	No
53	CD80	22758	13921	-0.096	-0.6167	No
54	PIAS2	1948 5102	14002	-0.102	-0.6202	No
55	FASLG	13789	14511	-0.153	-0.6465	No
56	BCL3	8654	14544	-0.157	-0.6470	No
57	ERC1	1013 17021 995 1136	14629	-0.171	-0.6502	No
58	FOS	21202	14800	-0.201	-0.6578	No
59	IL2RG	24096	14876	-0.214	-0.6602	No
60	STAT4	14251 9907	15027	-0.245	-0.6664	No
61	STAT6	19854 9909	15032	-0.245	-0.6647	No
62	JAK2	23893 9197 3706	15111	-0.267	-0.6669	No
63	STAT5A	20664	15113	-0.268	-0.6648	No
64	LCK	15746	15440	-0.368	-0.6796	No
65	TNFRSF1A	1181 10206	15447	-0.370	-0.6770	No
66	IFNG	19869	15478	-0.380	-0.6757	No
67	UBE2D3	7253	15487	-0.387	-0.6731	No
68	EBI3	23193	15490	-0.390	-0.6702	No
69	RELB	17942	15595	-0.439	-0.6724	No
70	IRF1	1336 1258 1433 9182	15819	-0.564	-0.6801	No
71	NOD2	6384	15978	-0.694	-0.6832	Yes
72	IL27RA	11949	15991	-0.707	-0.6784	Yes
73	REL	9716	16182	-0.909	-0.6816	Yes
74	MAPK9	1233 20903 1383	16314	-1.011	-0.6808	Yes
75	CYLD	18532	16380	-1.083	-0.6759	Yes
76	TYK2	12058 19215	16487	-1.199	-0.6723	Yes
77	MAP2K3	20856	16736	-1.563	-0.6735	Yes
78	JAK1	15827	16753	-1.590	-0.6620	Yes
79	RAN	5356 9691	16867	-1.732	-0.6546	Yes
80	GADD45G	21637	17072	-2.018	-0.6500	Yes
81	BIRC2	4397 4398	17074	-2.019	-0.6343	Yes
82	MAP2K6	20614 1414	17087	-2.043	-0.6191	Yes
83	PRKCA	20174	17337	-2.525	-0.6129	Yes
84	MAPK14	23313	17421	-2.682	-0.5966	Yes
85	GADD45B	19935	17545	-2.955	-0.5802	Yes
86	STAT2	19840	17576	-3.019	-0.5584	Yes
87	IL2RA	4918	17622	-3.145	-0.5363	Yes
88	JUN	15832	17687	-3.335	-0.5139	Yes
89	TGFB1	18332	17722	-3.435	-0.4890	Yes
90	NFKB1	15160	17789	-3.591	-0.4646	Yes
91	SOCS1	4522	17793	-3.598	-0.4368	Yes
92	MAP3K14	11998	17837	-3.699	-0.4104	Yes
93	NFKBIA	21065	17838	-3.699	-0.3816	Yes
94	ETV5	22630	17951	-4.075	-0.3560	Yes
95	RELA	23783	17959	-4.092	-0.3246	Yes
96	CREBBP	22682 8783	17993	-4.203	-0.2937	Yes
97	SYK	21636	18074	-4.548	-0.2626	Yes
98	BCL10	15397	18081	-4.569	-0.2274	Yes
99	TRAF6	5797 14940	18115	-4.665	-0.1929	Yes
100	TNFAIP3	19810	18134	-4.740	-0.1571	Yes
101	IL18	9172	18223	-5.139	-0.1219	Yes
102	STAT1	3936 5524	18294	-5.505	-0.0828	Yes
103	IL12A	4913	18393	-6.118	-0.0406	Yes
104	STAT3	5525 9906	18455	-6.760	0.0087	Yes